IFN-beta (Interferon-beta) is a cytokine that is produced by fibroblasts and pathogen-exposed dendritic cells, macrophages, and endothelial cells. It signals through the heterodimeric IFN-alpha/beta Receptor. IFN-beta-deficient mice show increased susceptibility to experimental autoimmune encephalomyelitis (EAE), a disease model of human multiple sclerosis (MS). Furthermore, IFN-beta has been shown to suppress the Th17 cell response in both MS and EAE and has commonly been used as a treatment for MS.
Recombinant Mouse IFN-beta (Mammalian) Protein
R&D Systems | Catalog # 12405-1
New Version Available:
8234-MB
NEW
A New rm IFN-beta is Available! It has lower endotoxin specifications, is made in-house, and is priced competitively!
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Key Product Details
- R&D Systems CHO-derived Recombinant Mouse IFN-beta (Mammalian) Protein (12405-1)
- Quality control testing to verify active proteins with lot specific assays by in-house scientists
- All R&D Systems proteins are covered with a 100% guarantee
Source
CHO
Accession Number
Applications
Bioactivity
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Product Specifications
Predicted Molecular Mass
19.6 kDa
Formulation, Preparation, and Storage
12405-1
| Formulation | 20 mM Sodium Phosphate, pH 6.4; 300 mM NaCl; 5% Glycerol; 0.1% bovine serum albumin (BSA) |
| Shipping | The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | After receipt, the product should be kept at -70°C or below for retention of full activity. Thaw product vial by incubation in cold tap water until just thawed - the contents of the tube should be apportioned in separate tubes so that freezing and thawing is kept to a minimum. Refreezing should be done on dry ice or in a dry ice/alcohol bath. Further dilution of the product should be in buffers containing protein such as 0.1% bovine serum albumin (BSA). |
Background: IFN-beta
Long Name
Interferon beta
Alternate Names
IFB, IFF, IFNB, IFNB1, IFNbeta
Gene Symbol
IFNB1
UniProt
Additional IFN-beta Products
Product Documents for Recombinant Mouse IFN-beta (Mammalian) Protein
Product Specific Notices for Recombinant Mouse IFN-beta (Mammalian) Protein
For research use only
Citations for Recombinant Mouse IFN-beta (Mammalian) Protein
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