IFN-beta (Interferon-beta) is a cytokine that is produced by fibroblasts and pathogen-exposed dendritic cells, macrophages, and endothelial cells. It signals through the heterodimeric IFN-alpha/beta Receptor. IFN-beta-deficient mice show increased susceptibility to experimental autoimmune encephalomyelitis (EAE), a disease model of human multiple sclerosis (MS). Furthermore, IFN-beta has been shown to suppress the Th17 cell response in both MS and EAE and has commonly been used as a treatment for MS.
Recombinant Mouse IFN-beta Protein
R&D Systems | Catalog # 12400-1
New Version Available:
8234-MB
NEW
A New rm IFN-beta is Available! It has lower endotoxin specifications, is made in-house, and is priced competitively!
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Key Product Details
- R&D Systems E. coli-derived Recombinant Mouse IFN-beta Protein (12400-1)
- Quality control testing to verify active proteins with lot specific assays by in-house scientists
- All R&D Systems proteins are covered with a 100% guarantee
Source
E. coli
Accession Number
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Formulation, Preparation, and Storage
12400-1
| Shipping | The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date. |
Background: IFN-beta
Long Name
Interferon beta
Alternate Names
IFB, IFF, IFNB, IFNB1, IFNbeta
Gene Symbol
IFNB1
UniProt
Additional IFN-beta Products
Product Documents for Recombinant Mouse IFN-beta Protein
Product Specific Notices for Recombinant Mouse IFN-beta Protein
For research use only
Citations for Recombinant Mouse IFN-beta Protein
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FAQs for Recombinant Mouse IFN-beta Protein
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Q: What are the differences between Recombinant Mouse IFN-beta Protein (Catalog # 8234-MB) and Recombinant Mouse IFN-beta Protein (Catalog # 12400-1)?
A: Catalog # 12400-1 is raised in E. coli and has an endotoxin specification of <1 EU/ug. Catalog # 8234-MB is raised in HEK293 cells, and it has a lower endotoxin specification of <0.10 EU per 1 ug of protein.
