(RS)-Baclofen

Tocris Bioscience | Catalog # 0417

Selective GABAB agonist
Tocris Bioscience

Key Product Details

Description

Selective GABAB agonist
View all GABA-B Receptor Agonists »

Product Description

(RS)-Baclofen is a selective GABAB receptor agonist. Skeletal muscle relaxant.

R-enantiomer also available.

Product Specifications for (RS)-Baclofen

Molecular Weight

213.66

Formula

C10H12ClNO2

Storage

Store at RT

Purity

≥99% (HPLC)

Chemical Name

(RS)-4-Amino-3-(4-chlorophenyl)butanoic acid

CAS Number

1134-47-0

PubChem ID

2284

InChI Key

KPYSYYIEGFHWSV-UHFFFAOYSA-N

SMILES

OC(CC(CN)C1=CC=C(Cl)C=C1)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
1eq. NaOH 100

Preparing Stock Solutions for (RS)-Baclofen

The following data is based on the product molecular weight 213.66.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.68 mL 23.40 mL 46.80 mL
5 mM 0.94 mL 4.68 mL 9.36 mL
10 mM 0.47 mL 2.34 mL 4.68 mL
50 mM 0.09 mL 0.47 mL 0.94 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 86 publications citing the usage of this product.

Product Documents for (RS)-Baclofen

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for (RS)-Baclofen

For research use only

Customer Reviews for (RS)-Baclofen (1)

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  • Baclofen effects on dopamine release
    Name: Anonymous
    Species: Mouse
    Assay Type: Ex Vivo
    Verified Customer | Posted 03/28/2018
    Effect was pretty small on striatal dopamine release. This may be due to low expression on terminals.
    Effects of GABAB agonism on electrically stimulated dopamine release was measured using fast scan cyclic voltammetry. Baclofen (30uM) was bath applied. This is a maximal concentration.
    (RS)-Baclofen 0417

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