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5 results for "GABA-B Receptor Agonists" in 产品
GABA-B Receptor Agonists
GABAB receptors are GPCRs composed of seven transmembrane domains and a large extracellular N-terminal, and are responsible for mediating the inhibitory effects of GABA, alongside ionotropic GABAA and GABAA-ρ receptors. They are composed of 850 - 960 amino acids, and are most similar in structure to metabotropic glutamate receptors (mGluRs).
These receptors are heterodimers of GABAB1 and GABAB2 subunits. The GABAB1 subunit hosts the binding site for GABA and other ligands, while the GABAB2...
Endogenous agonist
| Chemical Name: | γ-Aminobutyric acid |
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Selective GABAB agonist; active enantiomer of (RS)-Baclofen (Cat. No. 0417)
| Alternate Names: | STX 209 |
| Chemical Name: | (R)-4-Amino-3-(4-chlorophenyl)butanoic acid |
| Purity: | ≥99% |
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Caged GABA; inhibits neural activity
| Alternate Names: | RuBi-GABA-PMe3 |
| Chemical Name: | (bis(2,2'-Bipyridine-N,N')trimethylphosphine)-4-aminobutyric acid ruthenium complex sodium hexafluorophosphate salt |
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Highly potent GABAB agonist; also GABAA-ρ antagonist
| Alternate Names: | CGP 35024 |
| Chemical Name: | 3-Aminopropyl(methyl)phosphinic acid |
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Selective GABAB agonist
| Chemical Name: | (RS)-4-Amino-3-(4-chlorophenyl)butanoic acid |
| Purity: | ≥99% |
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