(RS)-(±)-Sulpiride

Tocris Bioscience | Catalog # 0894

Standard selective D2-like antagonist
Tocris Bioscience

Key Product Details

Description

Standard selective D2-like antagonist
View all Non-selective Dopamine Receptor Antagonists »

Product Description

(RS)-(±)-Sulpiride is a standard D2-like dopamine receptor antagonist.

S-enantiomer also available.

Product Specifications for (RS)-(±)-Sulpiride

Molecular Weight

341.42

Formula

C15H23N3O4S

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

(RS)-(±)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide

CAS Number

15676-16-1

PubChem ID

5355

InChI Key

BGRJTUBHPOOWDU-UHFFFAOYSA-N

SMILES

CCN1CCCC1CNC(=O)C1=C(OC)C=CC(=C1)S(N)(=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 34.14 100

Preparing Stock Solutions for (RS)-(±)-Sulpiride

The following data is based on the product molecular weight 341.42.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.93 mL 14.64 mL 29.29 mL
5 mM 0.59 mL 2.93 mL 5.86 mL
10 mM 0.29 mL 1.46 mL 2.93 mL
50 mM 0.06 mL 0.29 mL 0.59 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 12 publications citing the usage of this product.

Product Documents for (RS)-(±)-Sulpiride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for (RS)-(±)-Sulpiride

For research use only

Citations for (RS)-(±)-Sulpiride

Customer Reviews for (RS)-(±)-Sulpiride (2)

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  • Inhibition of Synaptic Transmission in the VP
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vivo
    Verified Customer | Posted 02/02/2020
    sulpiride (1 μM)
    (RS)-(±)-Sulpiride 0894
  • Sulpiride reverses quinpirole effects on dopamine release
    Name: Anonymous
    Species: Mouse
    Assay Type: Ex Vivo
    Verified Customer | Posted 03/28/2018
    We mix sulpiride at 2mM in ethanol. It goes into solution well.
    In voltammetry experiments measuring evoked dopamine release, quinpirole was used to activate D2 receptors to inhibit dopamine release. Sulpiride (600 nM) was applied afterward to reverse quinpirole effects.
    (RS)-(±)-Sulpiride 0894

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