SAMSN1 Antibody

Novus Biologicals | Catalog # NB300-976

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Western Blot, Peptide ELISA

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all SAMSN1 Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence IRLDTLSASLGRSC corresponding to N-Terminus according to NP_071419.2.

Specificity

Please note that the immunogen sequence is present in NP_071419.2 (and in AAK07746) but is no longer present in the latest reference sequence (NP_071419.3 at 05/10/05). This latest version has not been subject to final review by NCBI. This antibody may be recognising one particular isoform.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for SAMSN1 Antibody

Western Blot: SAMSN1 Antibody [NB300-976]

Western Blot: SAMSN1 Antibody [NB300-976]

Western Blot: SAMSN1 Antibody [NB300-976] - (1ug/ml) staining of Jurkat lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for SAMSN1 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:64000

Western Blot

0.5 - 1.5 ug/ml
Application Notes
WB: Approx. 48 kDa band observed in Jurkat T cell lysate (calculated MW of 41.7 kDa band according to NP_071419.2). The observed size is consistent with observations with competing products.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: SAMSN1

SAMSN1 is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains. It also contains several predicted consensus nuclear localization signals and a tyrosine kinase phosphorylation motif. Northern blot analysis has revealed expression of a 2.2kb SAMSN1 transcript in human immune tissues and hematopoietic cell types including normal bone marrow, acute myeloid leukemia, and multiple myeloma; low-level expression was seen in other tissues such as heart, brain, placenta, and lung. SAMSN1 has been shown to be up-regulated by B cell activation signals and is a participant in B cell activation and differentiation.

Alternate Names

HACS1gene with homology to KIAA0790 protein10NASH1, Hematopoietic adaptor containing SH3 and SAM domains 1, SAM and SH3 domain containing 1, SAM and SH3 domain containing 2, SAM domain, SH3 domain and nuclear localisation signals, 1, SAM domain, SH3 domain and nuclear localization signals 1, SAM domain, SH3 domain and nuclear localization signals protein 1, SAM domain-containing protein SAMSN-1, SH3D6B, SH3-SAM adaptor protein

Entrez Gene IDs

64092 (Human)

Gene Symbol

SAMSN1

UniProt

NP_071419.2 (Human)

Additional SAMSN1 Products

Product Documents for SAMSN1 Antibody

Certificate of Analysis

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Product Specific Notices for SAMSN1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for SAMSN1 Antibody

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