SART3 Antibody

Novus Biologicals | Catalog # NB100-1893

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all SART3 Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-MSNADFAKLFLRK corresponding to C-Terminus according to NP_055521.1.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for SART3 Antibody

Western Blot: SART3 Antibody [NB100-1893]

Western Blot: SART3 Antibody [NB100-1893]

Western Blot: SART3 Antibody [NB100-1893] - (1ug/ml) analysis of Daudi lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Applications for SART3 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:16000

Western Blot

0.01 - 0.03 ug/ml
Application Notes
WB: Approx. 170 kDa band observed in Daudi, Jurkat and MOLT4 lysates is reported in scientific literature (PMID: 10463607).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: SART3

The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing.

Alternate Names

DSAP1, hSART-3, KIAA0156squamous cell carcinoma antigen recognised by T cells 3, P100, p110, p110(nrb), RP11-13G14, SART-3, squamous cell carcinoma antigen recognized by T cells 3, squamous cell carcinoma antigen recognized by T-cells 3, Tat-interacting protein of 110 kDa, Tip110, TIP110MGC138188

Entrez Gene IDs

9733 (Human)

Gene Symbol

SART3

UniProt

NP_001036.1. (Human)

Additional SART3 Products

Product Documents for SART3 Antibody

Certificate of Analysis

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Product Specific Notices for SART3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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