SDS3 Antibody [CoraFluor™ 1]

Novus Biologicals | Catalog # NB100-257CL1

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Bovine (100%), Primate (100%). Backed by our 100% Guarantee.

Applications

Western Blot, Immunoprecipitation

Label

CoraFluor 1

Antibody Source

Polyclonal Goat IgG
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Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residues 175 and 225 of human Suppressor of Defective Silencing 3 using the numbering given in entry NP_071936.2 (GeneID 64426).

Reactivity Notes

Orangutan (100%).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Description

This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.

For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.

Scientific Data Images for SDS3 Antibody [CoraFluor™ 1]

SDS3 Antibody [CoraFluor™ 1]

Product Feature: CoraFluor Probes for TR-FRET

CoraFluor™ 1, amine reactive (Catalog:7920) and CoraFluor™ 2, amine reactive (Catalog # 7950) are terbium-based probes that have been developed for use as TR-FRET donors. They emit wavelengths compatible with commonly used fluorescent acceptor dyes such as BODIPY® (or BDY) and Janelia Fluor® dyes, FITC (Catalog # 5440), TMR and Cyanine 5 (Catalog # 5436). CoraFluor™ fluorescence is brighter and more stable in biological media than existing TR-FRET donors, leading to enhanced sensitivity and improved data generation. CoraFluor™ 1 exhibits excitation upon exposure to a 337 nm UV laser.

Applications for SDS3 Antibody [CoraFluor™ 1]

Application
Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Recommended applications are based on validated applications from the unconjugated base product NB100-257. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: SDS3

SDS3 is a subunit of the histone deacetylase-dependent SIN3A corepressor complex. The SIN3A corepressor complex functions to repress transcription through its interaction with histone deacetylases HDAC1 and HDAC2. SDS3 has been demonstrated to play a role in pericentric heterochromatin

Alternate Names

45 kDa Sin3-associated polypeptide, FLJ00052, SAP45suppressor of defective silencing 3 homolog (SDS3, S. cerevisiae), SDS3MGC104711, sin3 histone deacetylase corepressor complex component SDS3, sin3A-associated protein, 45kDa, suppressor of defective silencing 3 homolog (S. cerevisiae), Suppressor of defective silencing 3 protein homolog

Gene Symbol

SUDS3

Additional SDS3 Products

Product Documents for SDS3 Antibody [CoraFluor™ 1]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SDS3 Antibody [CoraFluor™ 1]

Sold for research purposes only under agreement from Massachusetts General Hospital, US Patent No. 12,134,721. A license is required for development of new commercial assay platforms (e.g., microarrays, microfluidics), diagnostic use or other unlicensed uses. Please contact Technical Support for further details: techsupport@bio-techne.com.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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