Se-NADA
Tocris Bioscience | Catalog # 7449
Key Product Details
Description
Wavelength
Product Description
Se-NADA is an orange fluorescent benzoselenadiazole D-amino acid (FDAA) for imaging bacteria. It is covalently incorporated into peptidoglycans in the cell walls of live bacteria. It also acts as a photosensitizer, bringing about bacterial cell death on exposure to visible light. Se-NADA is effective against both Gram-positive and Gram-negative bacteria. Ex/Em = 470/590 nm.Scientific Data Images for Se-NADA
Application of Se-NADA in B subtilis bacteria cells.
Fluorescence microscopy image of B subtilis bacterial cells treated with SeNADA (250 μM, red) proving incorporation of the D-amino acid into the peptidoglycans of the cell wall. Image kindly provided by Dr Erkin Kuru, Department of Genetics, Harvard Medical School, Boston.Licensing Information
Sold under license from the University of EdinburghOptical Data
| Emission Color | Orange |
| λabs | 470 nm |
| λem | 590 nm |
| Cell Permeable | Yes |
| Application | Fluorescence Microscopy |
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Product Specifications for Se-NADA
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 3.67 | 10 |
Preparing Stock Solutions for Se-NADA
The following data is based on the product molecular weight 366.62.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.28 mL | 136.38 mL | 272.76 mL |
| 0.5 mM | 5.46 mL | 27.28 mL | 54.55 mL |
| 1 mM | 2.73 mL | 13.64 mL | 27.28 mL |
| 5 mM | 0.55 mL | 2.73 mL | 5.46 mL |
Calculators
Background References
References are publications that support the biological activity of the product.
- Benson Photoactivatable metabolic warheads enable precise and safe ablation of target cells in vivo. Nat Commun 2021 PMID: 33888691
Product Documents for Se-NADA
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for Se-NADA
For research use only
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