CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
Simple Plex Control for Human CTLA-4
R&D Systems | Catalog # 898485
Control for use with Human and Non-Human Primate CTLA-4 Simple Plex Cartridge Kit
Loading...
Key Product Details
Species
Human, Non-human Primate
Applications
Control, Simple Plex Automated Immunoassay
Product Summary for Simple Plex Control for Human CTLA-4
INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human and NHP CTLA-4 concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.
Loading...
Background: CTLA-4
Long Name
Cytotoxic T-lymphocyte-associated Molecule 4
Alternate Names
CD152, CTLA4
Gene Symbol
CTLA4
Additional CTLA-4 Products
Product Documents for Simple Plex Control for Human CTLA-4
Certificate of Analysis
To download a Certificate of Analysis, please enter your Simple Plex catalog number and lot number in the search boxes below.
Product Specific Notices for Simple Plex Control for Human CTLA-4
For research use only
Customer Reviews for Simple Plex Control for Human CTLA-4
There are currently no reviews for this product. Be the first to review Simple Plex Control for Human CTLA-4 and earn rewards!
Have you used Simple Plex Control for Human CTLA-4?
Submit a review and receive an Amazon gift card!
$25/€18/£15/$25CAN/¥2500 Yen for a review with an image
$10/€7/£6/$10CAN/¥1110 Yen for a review without an image
Submit a review
Loading...