TAPI 1

Tocris Bioscience | Catalog # 6162

ADAM-17 (TACE) and MMP inhibitor
Tocris Bioscience

Key Product Details

Description

ADAM-17 (TACE) and MMP inhibitor
View all Synthetic Metalloprotease Inhibitors »

Product Description

TAPI 1 is a TACE/ADAM-17 and MMP inhibitor. Blocks shedding of TNF from cell membranes. Reduces pain-associated behavior in mice with a constructive mononeuropathy.

This product is typically reconstituted in DMSO.

Product Specifications for TAPI 1

Molecular Weight

499.60

Formula

C26H37N5O5

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)-L-alaninamide

CAS Number

163847-77-6

PubChem ID

9827273

InChI Key

AWNBSWDIOCXWJW-OWHMDLSXSA-N

SMILES

ONC(C[C@@H](CC(C)C)C(N[C@@H](CC1=CC(C=CC=C2)=C2C=C1)C(N[C@@H](C)C(NCCN)=O)=O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 14 publications citing the usage of this product.

Product Documents for TAPI 1

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for TAPI 1

For research use only

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