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Tenovin-1

Catalog #: 3365
1 Citation Datasheet / COA / SDS

Discontinued Product

3365 has been discontinued.
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Tenovin-1 | CAS No. 380315-80-0 | p53 Activators
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Description: Protects against MDM2-mediated p53 degradation

Chemical Name: N-[[[4-(Acetylamino)phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)benzamide

Purity: ≥99%

Product Details
Citations (1)
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Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Tenovin-1 is a p53 activator that protects against MDM2-mediated p53 degradation. Elevates levels of p53 and p21CIP/WAF1 and induces expression from an endogenous p53-dependent promoter. Exhibits potent antiproliferative activity in vitro.

Technical Data

M.Wt:
369.48
Formula:
C20H23N3O2S
Solubility:
Soluble to 25 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
380315-80-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citation for Tenovin-1

The citations listed below are publications that use Tocris products. Selected citations for Tenovin-1 include:

1 Citation: Showing 1 - 1

  1. Sirtuin Inhibitors Are Broadly Antiviral against Arboviruses.
    Authors: Hackett Et al.
    MBio  2019;10

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