Key Product Details

Species Reactivity

Bacteria

Applications

ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all Tetanus Toxin Primary Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to the amino acids 1300 - 1314 of the native molecule conjugated to Keyhole limpet Haemocyanin

Specificity

This product recognizes the tetanus toxin, a neurotoxin that inhibits neurotransmitter release.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for Tetanus Toxin Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

5.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Tetanus Toxin

Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the 76-Gln-|-Phe-77 bond of synaptobrevin-2. The precursor polypeptide is subsequently cleaved to yield subchains L and H. These remain linked by a disulfide bridge and are non-toxic after separation.

Alternate Names

Tentoxylysin

Gene Symbol

TETX

Additional Tetanus Toxin Products

Product Documents for Tetanus Toxin Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for Tetanus Toxin Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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