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TNF RI/TNFRSF1A Antibody Pair [Biotin]

Name: TNF RI/TNFRSF1A Antibody Pair [Biotin]
Brand: Novus Biologicals
SKU: NBP3-57712
Price: 899 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-57712

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Product Specifications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Assay Type

Sandwich ELISA

Sample Type

Cell culture supernatants. With minor modifications to the assay procedure, this ELISA can also be used in additional biological sample types reported in the literature reported in the literature, including serum, plasma, and tissue homogenates, providing flexibility for a broad range of immunology, inflammation, and translational research applications. (100 ul)

Reactivity

Guinea Pig

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Product Specifications

Description

The kit contains a capture antibody, detection antibody, and recombinant protein standard for assay development. These antibodies have been validated to function together in an ELISA format using the provided standard. Optimal buffers, antibody concentrations, incubation times, temperatures, and assay conditions have not been predetermined, allowing investigators to optimize assay sensitivity and dynamic range based on their specific sample type and experimental objectives. The quantities of kit components are not matched, and individual components may be purchased separately. This product is for research use only.

Sample Volume Required

100 ul

Conjugate

Biotin

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: TNF RI/TNFRSF1A

The protein encoded by the TNF Receptor I gene is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease. (provided by RefSeq)

Long Name

Tumor Necrosis Factor Receptor I

Alternate Names

CD120a, TNFRI, TNFRSF1A

Gene Symbol

TNFRSF1A

Additional TNF RI/TNFRSF1A Products

Product Documents for TNF RI/TNFRSF1A Antibody Pair [Biotin]

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Certificate of Analysis

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Product Specific Notices for TNF RI/TNFRSF1A Antibody Pair [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.