TransMoDE 3 Biotin

Tocris Bioscience | Catalog # 8829

Biotinylated angiopep-2, induces internalization and degradation of streptavidin in brain cell lines
Tocris Bioscience

Key Product Details

Description

Biotinylated angiopep-2, induces internalization and degradation of streptavidin in brain cell lines
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Product Description

TransMoDE 3 Biotin is a biotinylated peptide capable of inducing both the degradation of target protein via lysosomal proteolysis and their bidirectional transcytosis of streptavidin across the blood-brain barrier. TransMoDE 3 Biotin is derived from the peptide Angiopep-2 (Cat. No. 8828).

Product Specifications for TransMoDE 3 Biotin

Molecular Weight

2611.88

Formula

C118H167N31O35S

Storage

Store at -20°C

Purity

≥95% (HPLC)

InChI Key

SDTCWCCIHKRCLZ-MKHRACNQSA-N

SMILES

O=C(N[C@@H]([C@H](O)C)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC3=CC=C(C=C3)O)C(NCC(NCC(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CCCCNC(C)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CCCCNC(CCCC[C@@H]5SC[C@@](N6)([H])[C@]5([H])NC6=O)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC7=CC=C(C=C7)O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 1mg/ml in water

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for TransMoDE 3 Biotin

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for TransMoDE 3 Biotin

For research use only

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