TREML1/TLT-1 Antibody

Novus Biologicals | Catalog # NBP1-45208

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all TREML1/TLT-1 Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence CGPAQNPPNNQTPS corresponding to C-Terminus according to NP_835468.1.

Epitope

C-Terminus

Specificity

This antibody may cross-react with mouse TREML1 (GeneID: 71326; MW: 34.28 kDa).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for TREML1/TLT-1 Antibody

Western Blot: TREML1/TLT-1 Antibody [NBP1-45208]

Western Blot: TREML1/TLT-1 Antibody [NBP1-45208]

Western Blot: TREML1/TLT-1 Antibody [NBP1-45208] - (0.5ug/ml) Analysis of Human Bone Marrow lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Applications for TREML1/TLT-1 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:2000

Western Blot

0.3 - 1 ug/ml
Application Notes
WB: Approx. 30 kDa band observed in human bone marrow lysates (calculated MW of 32.7 kDa band according to NP_835468.1).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: TREML1/TLT-1

TREML1 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1(MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties. TREML1 enhances calciumsignaling in an SHP2 (PTPN11; MIM 176876)-dependent manner (Allcock et al., 2003 (PubMed 12645956); Barrow et al.,2004 (PubMed 15128762)).(supplied by OMIM)

Long Name

Triggering Receptor Expressed on Myeloid Cells-like 1

Alternate Names

TLT-1, TLT1

Entrez Gene IDs

340205 (Human)

Gene Symbol

TREML1

UniProt

NP_835468.1 (Human)

Additional TREML1/TLT-1 Products

Product Documents for TREML1/TLT-1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for TREML1/TLT-1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for TREML1/TLT-1 Antibody

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