TSH beta Antibody (Fc1005)

Novus Biologicals | Catalog # NBP1-78579

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunoprecipitation, Radioimmunoassay

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # Fc1005
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Product Specifications

Immunogen

Human Thyroid Stimulating Hormone

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for TSH beta Antibody (Fc1005)

Application
Recommended Usage

ELISA

1:100 - 1:2000

Immunoprecipitation

1:10 - 1:500

Radioimmunoassay

1:100 - 1:2000

Formulation, Preparation, and Storage

Purification

Ion exchange chromatography

Formulation

0.01M potassium phosphate, 0.135M NaCl, 1 mg/ml BSA, and 2.5mMKCl

Preservative

0.05% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TSH beta

Thyroid-stimulating hormone (TSH), also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones. TSH is a glycoprotein hormone composed of two subunits which are non-covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle-stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity.

Long Name

Thyroid-stimulating Hormone Subunit beta

Alternate Names

Thyrotropin beta, TSHB

Gene Symbol

TSHB

UniProt

Additional TSH beta Products

Product Documents for TSH beta Antibody (Fc1005)

Certificate of Analysis

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Product Specific Notices for TSH beta Antibody (Fc1005)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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