TWEAK/TNFSF12 Antibody Pair [Biotin]

Novus Biologicals | Catalog # NBP3-57732

Novus Biologicals
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Key Product Details

Assay Type

Sandwich ELISA

Sample Type

Cell culture supernatants. Additional biological sample types reported in the literature, including serum, plasma, bronchoalveolar lavage (BAL) fluid, synovial fluid, and tissue lysates. (100 ul)

Reactivity

Porcine
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Product Specifications

Description

Contains a capture antibody, detection antibody, and recombinant protein standard for assay development. These antibodies have been validated to function together in an ELISA format using the provided standard. Optimal buffers, antibody concentrations, incubation times, temperatures, and assay conditions have not been predetermined, allowing researchers to optimize assay sensitivity and dynamic range based on their specific sample type and experimental requirements. The quantities of components are not matched, and individual components may be purchased separately. This product is for research use only.

Sample Volume Required

100 ul

Conjugate

Biotin

Scientific Data Images for TWEAK/TNFSF12 Antibody Pair [Biotin]

TWEAK/TNFSF12 Antibody Pair [Biotin]

ELISA: TWEAK/TNFSF12 Antibody Pair [Biotin] [NBP3-57732] -

Representative standard curve for TWEAK/TNFSF12 Antibody Pair [Biotin] (NBP3-57732)

Kit Contents for TWEAK/TNFSF12 Antibody Pair [Biotin]

  • Capture Antibody (1 Set = <= 10 Plates; 2 Set = <= 20 Plates): (Catalog # <a href= /products/tweak-tnfsf12-antibody_nbp3-57639 >NBP3-57639</a>)
  • Detection Antibody (Biotinylated): (Catalog # <a href= "/products/tweak-tnfsf12-antibody_nbp3-57655" >NBP3-57655</a>)
  • Standard: (Catalog # <a href= "/products/tweak-tnfsf12-antibody_nbp3-57432" >NBP3-57432</a>)

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: TWEAK/TNFSF12

CD266 is a 14 kD transmembrane protein known as TWEAK receptor (TWEAK-R) or fibroblast growth factor inducible 14 (Fn14). It is member 12A of the tumor necrosis factor receptor superfamily (TNFRSF12A) expressed at low levels in a variety of tissues, such as heart, placenta, lung, muscle, and pancreas. TWEAK-R binds TWEAK (CD255) and interacts with the cytoplasmic proteins TRAF1, 2, and 3. The engagement of Fn14 can induce cell death and may play a role in inflammation, hepatocyte growth, and liver neoplasia. ITEM-4 antibody reacts with both mouse and human Fn14. It is useful for flow cytometric analysis.

Long Name

TNF-like and Weak Inducer of Apoptosis

Alternate Names

TNFSF12

Gene Symbol

TNFSF12

Additional TWEAK/TNFSF12 Products

Product Documents for TWEAK/TNFSF12 Antibody Pair [Biotin]

Certificate of Analysis

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Product Specific Notices for TWEAK/TNFSF12 Antibody Pair [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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