UNC 926 hydrochloride

Tocris Bioscience | Catalog # 4516

L3MBTL1 domain inhibitor
Tocris Bioscience
Discontinued Product
4516 has been discontinued. View all Additional Transcription Factor Compounds products.

Key Product Details

Description

L3MBTL1 domain inhibitor
View all Additional Transcription Factor Compounds »

Product Description

UNC 926 hydrochloride is a methyl-lysine (Kme) reader domain inhibitor; binds to the MBT domain of the L3MBTL1 protein (Kd = 3.9 μM). Selectively inhibits the L3MBTL13XMBT-H4K20me1 interaction in a peptide pull down assay.

Product Specifications for UNC 926 hydrochloride

Molecular Weight

373.72

Formula

C16H21BrN2O.HCl

Storage

Desiccate at RT

Purity

≥99% (HPLC)

Chemical Name

(3-Bromophenyl)[4-(1-prrolidinyl)-1-piperidinyl]methanone hydrochloride

CAS Number

1782573-49-2

PubChem ID

90488947

InChI Key

DPPMBBHOXQOMJI-UHFFFAOYSA-N

SMILES

BrC1=CC=CC(C(N2CCC(N3CCCC3)CC2)=O)=C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 37.37 100
DMSO 37.37 100

Preparing Stock Solutions for UNC 926 hydrochloride

The following data is based on the product molecular weight 373.72.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.68 mL 13.38 mL 26.76 mL
5 mM 0.54 mL 2.68 mL 5.35 mL
10 mM 0.27 mL 1.34 mL 2.68 mL
50 mM 0.05 mL 0.27 mL 0.54 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

  • Herold Structure-activity relationships of methyl-lysine reader antagonists. Med.Chem.Comm

Product Documents for UNC 926 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for UNC 926 hydrochloride

For research use only

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