URI Antibody

Novus Biologicals | Catalog # NB100-59777

Novus Biologicals
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Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Human

Applications

Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all URI Primary Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 350 and 400 of human RNA polymerase II, subunit 5 (RPB5)-mediating protein using the numbering given in entry BAA34781.1 (GeneID 8725).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for URI Antibody

Western Blot: URI Antibody [NB100-59777]

Western Blot: URI Antibody [NB100-59777]

Western Blot: URI Antibody [NB100-59777] - Detection of Human RMP on HeLa whole cell lysate using NB100-59777. RMP was also immunoprecipitated by rabbit anti-RMP antibody NB100-59778.

Applications for URI Antibody

Application
Recommended Usage

Immunoprecipitation

1:10-1:500

Western Blot

1:2000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: URI

The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Alternate Names

chromosome 19 open reading frame 2, FLJ10575, NNX3RPB5-mediating protein, Protein NNX3, RMPunconventional prefoldin RPB5 interactor, RNA polymerase II subunit 5-mediating protein, URIRNA polymerase II, subunit 5-mediating protein

Entrez Gene IDs

8725 (Human)

Gene Symbol

URI1

UniProt

BAA34781.1 (Human)

Additional URI Products

Product Documents for URI Antibody

Certificate of Analysis

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Product Specific Notices for URI Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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