USH1C Antibody

Novus Biologicals | Catalog # NB100-1405

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Bovine

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Validated:

Western Blot, ELISA

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all USH1C Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence DRKVAREFRHKVD-C corresponding to N-Terminus according to NP_710142.1.

Reactivity Notes

Bovine reactivity reported in scientific literature (PMID: 20058854).

Localization

Nuclear

Specificity

This antibody is expected to recognize both reported isoforms (NP_005700.2 and NP_710142.1).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for USH1C Antibody

Western Blot: USH1C Antibody [NB100-1405]

Western Blot: USH1C Antibody [NB100-1405]

Western Blot: USH1C Antibody [NB100-1405] - (0.1ug/ml) staining of HEK293 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for USH1C Antibody

Application
Recommended Usage

ELISA

Detection limit 1:128000

Western Blot

0.1 - 0.3 ug/ml
Application Notes
WB: Approx. 75 kDa band observed in HEK293 lysates (calculated MW of 62.2 kDa band according to NP_005700.2).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: USH1C

USH1C may be involved in protein-protein interaction. Defects in USH1C are the cause of Usher syndrome type 1c. It is an autosomal recessive sensory defect involving congenital profound sensorineural deafness, vestibular dysfunction, and blindness due to progressive retinitis pigmentosa. Defects in USH1C are also the cause of nonsyndromic recessive deafness.

Alternate Names

AIE75, AIE-75, Antigen NY-CO-38/NY-CO-37, Autoimmune enteropathy-related antigen AIE-75, deafness, autosomal recessive 18, DFNB18, harmonin, NY-CO-37, NY-CO-38, PDZ-45, PDZ73, PDZ-73, PDZ-73/NY-CO-38, Protein PDZ-73, Renal carcinoma antigen NY-REN-3, ush1cpst, Usher syndrome 1C (autosomal recessive, severe), Usher syndrome type-1C protein

Entrez Gene IDs

10083 (Human); 72088 (Mouse); 308596 (Rat)

Gene Symbol

USH1C

UniProt

NP_005700. (Human)

Additional USH1C Products

Product Documents for USH1C Antibody

Certificate of Analysis

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Product Specific Notices for USH1C Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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