Q: I was wondering if you know of any blocking antibodies against IL-6 or VEGF-C that can be used in cell culture to quench these cytokines?

A: We have no antibodies that are currently known to show blocking antibodies to VEGF-C. Please see this link to our IL-6 antibodies with blocking/neutralizing activity can be found at this link.

VEGF-C Antibody (107/A11)

Novus Biologicals | Catalog # NBP2-36288

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Product Documents

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Calculators
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human, Rat

Applications

Western Blot, ELISA, Sandwich ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG_2A Clone # 107/A11

View all VEGF-C Primary Antibodies »

Product Specifications

Immunogen

Recombinant human VEGF-C

Clonality

Monoclonal

Host

Mouse

Isotype

IgG_2A

Description

Novus Biologicals Mouse VEGF-C Antibody (107/A11) (NBP2-36288) is a monoclonal antibody validated for use in WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for VEGF-C Antibody (107/A11)

Sandwich ELISA: VEGF-C Antibody (107/A11) [NBP2-36288] - Recombinant human VEGF-C as standard. Mouse anti-human VEGF-C #9/G10 was used as capture antibody, Biotinylated mouse anti-human VEGF-C #107/A11 was used for detection.

Applications for VEGF-C Antibody (107/A11)

Application

Recommended Usage

ELISA

1:100 - 1:2000

Sandwich ELISA

1:100-1:2000

Western Blot

1:100 - 1:2000

Formulation, Preparation, and Storage

Purification

Protein G purified

Reconstitution

Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.

Formulation

PBS and 50x BSA

Preservative

0.02% Sodium Azide

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Background: VEGF-C

Vascular endothelial growth factors (VEGFs), also known as vasculotropins, are a family of closely related growth factors having a conserved pattern of eight cysteine residues and sharing common VEGF receptors. VEGFs stimulate the proliferation of endothelial cells, induce angiogenesis, promote cell migration, increase vascular permeability, and inhibit apoptosis. The mitogenic activity of VEGFs appears to be mediated by specific VEGF receptors. The target cell specificity of VEGF is restricted to vascular endothelial cells. Vascular Endothelial Growth Factor C (VEGFC) is a member of the VEGF subfamily of PDGF-related growth factors. It is the ligand for Flt4 (VEGFR3) and KDR (VEGFR2). VEGFC binds Flt4 and induces tyrosine autophosphorylation of VEGFR3 and VEGFR2. VEGFC also stimulates the migration of bovine capillary endothelial cells in collagen gel. It is a specific growth factor for the lymphatic vascular system and mediates lymphangiogenesis. VEGFC is abundantly expressed in heart and skeletal muscle. Other tissues such as lung and kidney also express VEGFC. The human VEGFC gene is located on chromosome 4q34.

Long Name

Vascular Endothelial Growth Factor C

Alternate Names

VEGFC

Gene Symbol

VEGFC

Additional VEGF-C Products

Product Documents for VEGF-C Antibody (107/A11)

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Product Specific Notices for VEGF-C Antibody (107/A11)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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