Infection by mosquito-borne West Nile Virus can cause severe neurological disease and can be epidemic. Two non-structural proteins, NS3 and NS2b, play an essential role in viral replication, and are therefore potential targets for treatment and prevention of West Nile Virus disease. NS3 consists of a trypsin-like serine protease with a catalytic triad (His51, Asp75, Ser135) and a putative helicase. Requiring NS2b as the cofactor, NS3 protease processes viral polyprotein precursor.
wnvNS3 Protease Antibody (991926) [Janelia Fluor® 549]
Novus Biologicals | Catalog # FAB29073I
Key Product Details
Species Reactivity
Viral
Applications
ELISA
Label
Janelia Fluor 549
Antibody Source
Monoclonal Mouse IgG1 Clone # 991926
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Product Specifications
Immunogen
E. coli-derived Viral wnvNS3 Protease
sequences: rwnvNS2b 1-48, rwnvNS3 1-184
sequences: rwnvNS2b 1-48, rwnvNS3 1-184
Specificity
Detects viral wnvNS3 Protease in direct ELISAs.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Applications for wnvNS3 Protease Antibody (991926) [Janelia Fluor® 549]
Application
Recommended Usage
ELISA
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: wnvNS3 Protease
Long Name
West Nile Virus NS3 Protease
Additional wnvNS3 Protease Products
Product Documents for wnvNS3 Protease Antibody (991926) [Janelia Fluor® 549]
Product Specific Notices for wnvNS3 Protease Antibody (991926) [Janelia Fluor® 549]
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Related Research Areas
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
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- View all Protocols, Troubleshooting, Illustrated assays and Webinars
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