XPF Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-47427

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

DNA repair endonuclease XPF. (Uniprot# Q92889)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for XPF Antibody - BSA Free

XPF Antibody - BSA Free

Western Blot: XPF Antibody - BSA Free [NBP3-47427] -

Western Blot: XPF Antibody - BSA Free [NBP3-47427] - U-251 MG cells were subjected to SDS PAGE followed by western blot with (XPF antibody) at dilution of 1:1000

Applications for XPF Antibody - BSA Free

Application
Recommended Usage

Western Blot

1:500-1:2000
Application Notes
Theoretical Molecular Weight is 110-120 kDa, 55-60 kDa

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: XPF

XPF/ERCC4 is suggested to play a role in the repair of DNA double-strand breaks (DSB), homologous recombination, and gene conversion via single-strand annealing (SSA). XPF/ERCC4 is an endonuclease that incises 5-prime DNA. Defects in XPF/ERCC4 cause xeroderma pigmentosum VI (XP6) an autosomal recessive disease characterized by hypersensitivity to sunlight and a predisposition to skin cancer as well as neurological abnormalities. Defects in XPF/ERCC4 are also responsible for XFE progeroid syndrome, a syndrome characterized by dwarfism, cachexia, and microcephaly.

Long Name

Xeroderma Pigmentosum F

Alternate Names

ERCC4

Gene Symbol

ERCC4

Additional XPF Products

Product Documents for XPF Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for XPF Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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