Z-DEVD-FMK

Tocris Bioscience | Catalog # 2166

Cell-permeable, irreversible caspase-3 inhibitor
Tocris Bioscience
Discontinued Product
2166 has been discontinued. An alternative/replacement product is available: 8009. View all Caspase Inhibitors products.

Key Product Details

Description

Cell-permeable, irreversible caspase-3 inhibitor
View all Caspase Inhibitors »

Product Description

Z-DEVD-FMK is a cell-permeable, irreversible inhibitor of caspase-3/CPP32; inhibits tumor cell apoptosis. Neuroprotective in rat hippocampus following seizures in vivo.

Product Specifications for Z-DEVD-FMK

Molecular Weight

668.67

Formula

C30H41FN4O12

Storage

Store at -20°C

Chemical Name

Benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethylketone

CAS Number

210344-95-9

PubChem ID

16760394

InChI Key

GBJVAVGBSGRRKN-JYEBCORGSA-N

SMILES

[H]N([C@@H](CC(=O)OC)C(=O)N[C@@H](CCC(=O)OC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)OC)C(=O)CF)C(=O)OCC1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 13.37mg/ml in DMSO

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 16 publications citing the usage of this product.

Product Documents for Z-DEVD-FMK

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Z-DEVD-FMK

For research use only

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