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5-HT2C Receptor Agonists

Serotonin 5-HT2C receptors, previously known as 5-HT1C receptors, are located primarily in the choroid plexus, cortex, limbic system and basal ganglia. 5-HT2C receptors play a role in CSF volume regulation, thermoregulation, penile erection and anxiety. The human 5-HT2C receptor gene has been localized to chromosome X (Xq24).

Selective D1-like antagonist; also 5-HT2C agonist and Kir3 channel blocker

Alternate Names: (R)-(+)-SCH 23390 hydrochloride
Chemical Name: (R)-(+)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride
Purity: ≥98%
Selective D1-like antagonist; also 5-HT2C agonist and Kir3 channel blocker
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