8 results for "Additional NMDA Receptor Compounds Small Molecules and Peptides" in 产品
Additional NMDA Receptor Compounds Small Molecules and Peptides
NMDA receptors are expressed alongside AMPA receptors on the postsynaptic membrane of excitatory synapses, where they initiate a two-component excitatory postsynaptic potential (EPSP). The activation of AMPA receptors produces a current that has rapid onset and decay, while activation of NMDA receptors leads to a current with slower onset and decay. The slow decay of NMDA-mediated currents is due to the slow dissociation of glutamate from NMDA receptors, compared with AMPA receptors. Unlike ...
NMDA potentiator; also GABAA inhibitor and TRPM3 activator
| Chemical Name: | (3β)-3-(Sulfooxy)-pregn-5-en-20-one sodium salt |
Open-channel blocker of AMPA currents; selective for non-GluA2-containing receptors
| Chemical Name: | N,N,H,-Trimethyl-5-[(tricyclo[3.3.1.13,7]dec-1-ylmethyl)amino]-1-pentanaminiumbromide hydrobromide |
| Purity: | ≥98% |
Endogenous potentiator of NMDA receptors
| Chemical Name: | Aminoethanoic acid |
Potentiator of NMDA recepors; acts at glycine site
Potentiator of NMDA receptors containing GluN2C/GluN2D
| Chemical Name: | (3-Chlorophenyl) [3,4-dihydro-6,7-dimethoxy-1-[(4-methoxyphenoxy)methyl]-2(1H)-isoquinolinyl]methanone |
| Purity: | ≥98% |
Modulator at polyamine site
| Chemical Name: | N,N'-Bis(3-aminopropyl)-1,4-butanediamine tetrahydrochloride |
Cognitive enhancer
| Alternate Names: | DM 9384 |
| Chemical Name: | N-(2,6-Dimethylphenyl)-2-oxo-1-pyrrolidineacetamide |
| Purity: | ≥99% |
Enhances AMPA currents: antidepressant
| Chemical Name: | cis-2-Amino-2-(2-chlorophenyl)-6-hydroxycyclohexanone hydrochloride |
| Purity: | ≥98% |