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1 result for "Additional VDR-like Receptor Compounds Small Molecules and Peptides" in 产品
Additional VDR-like Receptor Compounds Small Molecules and Peptides
Vitamin D receptors (VDRs) are members of the NR1I family, which also includes pregnane X receptors (PXR) and constitutive androstane receptors (CAR). They form heterodimers with members of the retinoid X receptor family. VDR is expressed in the intestine, thyroid and kidney.
VDRs repress expression of 1α-hydroxylase (the proximal activator of 1,25(OH)2D3) and induce expression of the 1,25(OH)2D3 inactivating enzyme CYP24. Also, it has recently been identified as an additional bile acid ...
Vitamin D3 analog
| Alternate Names: | MC 903 |
| Chemical Name: | (1α,3β,5Z,7E,22E,24S)-24-Cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1,3,24-triol |
| Purity: | ≥98% |
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