1 result for "Bcl-2 Family Inhibitors" in 产品

Bcl-2 Family Inhibitors

Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. They comprise a large protein family and all members contain at least one of four BH (Bcl-2 homology) domains. Certain members such as Bcl-2, Bcl-XL and Mcl-1 are antiapoptotic, whilst others (Bax, Bak, Bok) are proapoptotic.

The proapoptotic group of Bcl-2 proteins can be further sub-divided into the structurally diverse 'BH3' only proteins (including Bid, NOXA, PUMA and Bad) and the multidomain ...

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Molecular glue; induces degradation of BCL6

Chemical Name: rel-5-[[5-Chloro-2-[(3R,5S)-4,4-difluoro-3,5-dimethyl-1-piperidinyl]-4-pyrimidinyl]amino]-1,3-dihydro-3-(3-hydroxy-3-methylbutyl)-1-methyl-2H-benzimidazol-2-one
Purity: ≥98%
Molecular glue; induces degradation of BCL6
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