113 results for "BMPR-IB/ALK-6" in 产品

BMPR-IB/ALK-6 Products

Cellular responses to bone morphogenetic proteins (BMPs) are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. There are seven known type I serine/threonine kinases and five mammalian type II serine/threonine kinase receptors that function in TGF-beta superfamily signal transduction. The type II receptors for TGF-beta and activin bind ligands with high affinity by themselves. In contrast, BMPR-II binding to BMP-2, BMP-4, and BMP-7 is facilitated by the presence of the type I receptor. The type I receptors are also known as activin receptor-like kinases or ALKs.

Potent and selective ALK2 and ALK3 inhibitor; inhibits BMP4 signaling; promotes neural induction of hPSCs

GMP Version Available: TB6053-GMP
GMP
Chemical Name: 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Purity: ≥98%
Application of LDN 193189 in motor neurons differentiated from iPSCs
(2)
Loading...

Potent AMPK inhibitor; also BMP type I receptor inhibitor

Alternate Names: Compound C,BML-275
Chemical Name: 6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidine dihydrochloride
Purity: ≥98%
Potent AMPK inhibitor; also BMP type I receptor inhibitor
Loading...
Reactivity: Human
Source: NS0
Accession #: O00238
Applications: Bioactivity
R&D Systems Recombinant Proteins and Enzymes
Loading...
Reactivity: Human
Details: Mouse IgG2B Monoclonal Clone #477914
Applications: Flow, ICC/IF, CyTOF-ready
Detection of BMPR‑IB/ALK‑6 antibody in PC‑3 Human Cell Line antibody by Flow Cytometry.
(3)
Loading...
Reactivity: Human, Mouse, Rat, Bovine
Details: Rabbit IgG Polyclonal
Applications: IHC, WB
Western Blot: BMPR-IB/ALK-6 Antibody [NBP2-14889]
(6)
Loading...
Reactivity: Mouse
Source: NS0
Accession #: P36898
Applications: Bioactivity
R&D Systems Recombinant Proteins and Enzymes
Loading...
Reactivity: Human
Details: Mouse IgG2B Monoclonal Clone #477914
Applications: Flow
Detection of BMPR-IB/ALK-6 antibody in PC-3 Human Cell Line antibody by Flow Cytometry.
(3)
Loading...
Reactivity: Human
Details: Mouse IgG2B Monoclonal Clone #477914
Applications: Flow
Detection of BMPR-IB/ALK-6 antibody in PC-3 Human Cell Line antibody by Flow Cytometry.
(2)
Loading...

Type I BMP receptor inhibitor

Chemical Name: 4-[6-[4-[2-(4-Morpholinyl)ethoxy]phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline
Purity: ≥98%
Type I BMP receptor inhibitor
Loading...

Potent TGF-βRI inhibitor

Chemical Name: 4-[[4-[(2.6-Dimethyl-3-pyridinyl)oxy]-2-pyridinyl]amino]benzenesulfonamide
Purity: ≥98%
Potent TGF-βRI inhibitor
Loading...
Reactivity: Human
R&D Systems VersaClone cDNA Plasmids
Loading...
Reactivity: Mouse
R&D Systems VersaClone cDNA Plasmids
Loading...
Reactivity: Human
Details: Mouse IgG1 kappa Monoclonal Clone #2F3
Applications: WB, ELISA, Mycoplasma
Western Blot: BMPR-IB/ALK-6 Antibody (2F3) [H00000658-M01]
(3)
Loading...
Reactivity: Human, Mouse
Details: Mouse IgG2a Kappa Monoclonal Clone #2E2
Applications: WB, ELISA
Western Blot: BMPR-IB/ALK-6 Antibody (2E2) [H00000658-M07]
(3)
Loading...

Sterile-filtered 10 mM solution of LDN 193189 pre-dissolved in water

Chemical Name: 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Purity: ≥97%
Sterile-filtered 10 mM solution of LDN 193189 pre-dissolved in water
Loading...
Results Per Page
5 10 25 50