20 results for "Cell Cycle Inhibitors Small Molecules and Peptides" in 产品
Cell Cycle Inhibitors Small Molecules and Peptides
Cell cycle inhibitors slow or stop cell cycle progression through various mechanisms. Cell cycle arrest can be induced at different stages, decreasing the rate of cell division and the number of actively cycling cells.
mRNA splicing inhibitor; antitumor
| Chemical Name: | (4R,7R,8S,9E,11S,12S)-8-(Acetyloxy)-4,7-dihydroxy-12-[(1E,3E,5S)-6-[(2R,3R)-3-[(1R,2S)-2-hydroxy-1-methylbutyl]-2-oxiranyl]-1,5-dimethyl-1,3-hexadien-1-yl]-7,11-dimethyloxacyclododec-9-en-2-one |
| Purity: | ≥95% |
Cytotoxic agent
| Chemical Name: | N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid |
| Purity: | ≥98% |
Potent and selective Cdc7 inhibitor
| Alternate Names: | BMS 863233 |
| Chemical Name: | 8-Chloro-2-(2S)-2-pyrrolidinylbenzofuro[3,2-d]pyrimidin-4(3H)-one hydrochloride |
| Purity: | ≥98% |
Cdk inhibitor
| Alternate Names: | CYC 202,Seliciclib |
| Chemical Name: | (2R)-2-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol |
| Purity: | ≥98% |
Potent and selective CDK7 inhibitor; induces cell cycle arrest
| Chemical Name: | N-[(1S)-2-(Dimethylamino)-1-phenylethyl]-4,6-dihydro-6,6-dimethyl-3-[[4-[(1-oxo-2-propen-1-yl)amino]benzoyl]amino]pyrrolo[3,4-c]pyrazole-5(1H)-carboxamide |
| Purity: | ≥95% |
Stimulates RhoA activation; antiproliferative agent that slows cell cycle progression
| Chemical Name: | (2S,3R,4S,4aR)-3,4,4a,5-Tetrahydro-2,3,4,7-tetrahydroxy-(1,3)dioxolo(4,5-j)phenanthridin-6(2H)-one |
| Purity: | ≥98% |
Cdk inhibitor; potently inhibits cdk1, 2, 5 and 9
| Chemical Name: | 4-[2-Methyl-1-(1-methylethyl)-1H-imidazol-5-yl]-N-[4-(methylsulfonyl)phenyl]-2-pyrimidinamine |
| Purity: | ≥98% |
Soluble guanylyl cyclase (sGC) activator; induces G1 cell cycle arrest
| Chemical Name: | 3-(5'-Hydroxymethyl-2'-furyl)-1-benzyl indazole |
| Purity: | ≥98% |
Inhibits c-Myc-Max dimerization
| Chemical Name: | 5-[(4-Ethylphenyl)methylene]-2-thioxo-4-thiazolidinone |
| Purity: | ≥98% |
BET bromodomain inhibitor; arrests cell cycle at G1 phase
| Alternate Names: | TEN 010 |
| Chemical Name: | (6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide |
| Purity: | ≥98% |
Potent cdk inhibitor
| Chemical Name: | 3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol |
| Purity: | ≥98% |
Potent and selective mTOR inhibitor
| Chemical Name: | N-[4-[4-(4-Morpholinyl)-1-[1-(3-pyridinylmethyl)-4-piperidinyl]-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]-carbamic acid methyl ester dihydrochloride |
| Purity: | ≥98% |
SMO antagonist; acts at different binding site to cyclopamine (Cat No. 1623)
| Chemical Name: | 4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one |
| Purity: | ≥98% |
Potent covalent CDK14 and CDK16 inhibitor; also inhibits other TAIRE kinase family members
| Chemical Name: | N-[1-[[3-[[(2E)-4-(Dimethylamino)-1-oxo-2-buten-1-yl]amino]phenyl]sulfonyl]-4-piperidinyl]-4-[(2,4,6- trichlorobenzoyl)amino]-1H-pyrazole-3-carboxamide |
| Purity: | ≥98% |
Potent CDK14 and CDK16 inhibitor; displays reversible inhibition of CDK14
| Chemical Name: | N-(1-((3-(4-(Dimethylamino)butanamido)phenyl)sulfonyl)piperidin-4-yl)-4-(2,4,6-trichlorobenzamido)-1H-pyrazole-3-carboxamide |
| Purity: | ≥98% |
Selective exportin-1 (XPO1/CRM1) inhibitor
| Chemical Name: | (2Z)-3-[3-[3,5-Bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-2-propenoic acid 2-(2-pyridinyl)hydrazide |
| Purity: | ≥98% |
High affinity Bcl-2 family inhibitor; proapoptotic, senolytic and antitumor
| Chemical Name: | 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide |
| Purity: | ≥98% |
Potent protein synthesis inhibitor
| Alternate Names: | Dehydrodidemnin B,DDB |
| Purity: | ≥98% |
Potent and selective MST3 kinase binding inhibitor
| Chemical Name: | 8-(4-Aminobutyl)-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(1,3-dihydroxypropan-2-ylamino)pyrido[2,3-d]pyrimidin-7-one trihydrochloride |
| Purity: | ≥98% |
Potent and selective CK2α and CK2α' inhibitor. Also blocks CK2-dependent HIF-1α transcription, causes cell-cycle arrest, induces apoptosis in cancer cells and induces stem cell reprogramming
| Alternate Names: | Silmitasertib |
| Chemical Name: | Sodium 5-[(3-Chlorophenyl)amino]benzo[c]-2,6-naphthyridine-8-carboxylate |
| Purity: | ≥98% |
