4 results for "CHRM4" in 产品
CHRM4 Products
Muscarinic acetylcholine receptor M4 is an Acetylcholine Receptor. Unlike muscarinic receptor M2, the M4 receptor is not involved in smooth muscle contraction. The clinical relevance of this receptor is unknown. However, mouse studies have linked it to adenylyl cyclase inhibition. Muscarinic acetylcholine receptor M4 has been reported to be expressed in many regions of the rat brain, particularly the striatum and hippocampus. ESTs have been isolated from human breast and eye libraries.
Positive allosteric modulator of M4 receptors
| Alternate Names: | ML 108 |
| Chemical Name: | 3-Amino-N-(4-methoxybenzyl)-4,6-dimethylthieno[2,3-b]pyridine carboxamide |
| Purity: | ≥98% |
Selective positive allosteric modulator of M4 receptors
| Chemical Name: | 3-Amino-N-[(4-chlorophenyl)methyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide |
| Purity: | ≥98% |
Positive allosteric modulator of M2 and M4 receptors
| Chemical Name: | 3-Amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methyl-1-piperazinyl)-2-oxoethoxy]-thieno[2,3-b]pyridine-2-carboxamide |
| Purity: | ≥98% |
Selective positive allosteric modulator of M4 receptors; active in vivo; antipsychotic
| Chemical Name: | 3-Amino-5-chloro-N-cyclopropyl-6-methoxy-4-methylthieno[2,3-b]pyridine-2-carboxamide |
| Purity: | ≥98% |
