141 results for "cIAP-2/HIAP-1" in 产品

cIAP-2/HIAP-1 Products

cIAP-2 (also known as MIHC and HIAP-1) is a member of the inhibitor of apoptosis (IAP) family of proteins that inhibit the proteolytic activity of mature caspases. cIAP-2 has 3 BIR (baculovirus inhibitor of apoptosis) domains, a RING finger domain, and a caspase recruitment domain (CARD). cIAP-2 inhibits caspases through the direct interaction of its BIR domain with the active caspase. Caspase activity may be restored through interactions with the Reaper like motif on mitochondrial proteins such as SMAC/Diablo or HtrA2/Omi. cIAP-2 is reported to be cleaved by HtrA2/Omi.

Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, ICC/IF, Simple Western
Western Blot: cIAP-2/HIAP-1 AntibodyBSA Free [NBP1-27972]
(5)
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Contains 4 membranes - each spotted in duplicate with 35 different apoptosis antibodies

Reactivity: Human
Determination of Relative Levels of Human Apoptosis-related Proteins Using Proteome Profiler Human Apoptosis Array Kit.
(2)
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Reactivity: Human, Mouse
Details: Rabbit IgG Polyclonal
Applications: WB, ICC/IF
Immunocytochemistry/ Immunofluorescence: cIAP-2/HIAP-1 Antibody [NBP1-90132]
(3)
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Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, IP
Immunohistochemistry: cIAP-2/HIAP-1 Antibody [NB100-56132]
(2)
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Reactivity: Human
Source: E. coli
Accession #: Q13489
Applications: Inhibition Activity
R&D Systems Recombinant Proteins and Enzymes
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Dimeric Smac mimetic; potent IAP inhibitor

Chemical Name: 3,3'-[2,4-Hexadiyne-1,6-diylbis[oxy[(1S,2R)-2,3-dihydro-1H-indene-2,1-diyl]]]bis[N-methyl-L-alanyl-(2S)-2-cyclohexylglycyl-L-prolinamide
Purity: ≥97%
Dimeric Smac mimetic; potent IAP inhibitor
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Reactivity: Human
Applications: AC
cIAP-2/HIAP-1 Antibody Blocking Peptide
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Reactivity: Human
Applications: AC
cIAP-2/HIAP-1 Antibody Blocking Peptide
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Potent Lys-covalent pan-IAP inhibitor

Chemical Name: (R)-1-((S)-1-((S)-2-Cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)pyrrolidine-2-carboxamido)-2,3-dihydro-1H-inden-4-yl sulfurofluoridate
Purity: ≥95%
Potent Lys-covalent pan-IAP antagonist
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Monovalent IAP antagonist

Chemical Name: (2S,4S)-1-((S)-2-Cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)-4-phenoxy-N-((R)-1,2,3,4-tetrahydronaphthalen-1-yl)pyrrolidine-2-carboxamide
Purity: ≥97%
Selective cIAP1 Degrader (PROTAC®)
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Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #OTI1A9
Applications: WB, Flow, CyTOF-ready
Western Blot: cIAP-2/HIAP-1 Antibody (OTI1A9)Azide and BSA Free [NBP2-70184]
(2)
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Recombinant Monoclonal Antibody

Reactivity: Human
Details: Rabbit IgG Monoclonal Clone #SR2173
Applications: IHC, WB, ICC/IF, IP
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