881 results for "CTLA-4" in 产品

CTLA-4 Products

CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.

Reactivity: Human
Source: Sf 21 (baculovirus)
Accession #: Q6GR94
Applications: Bioactivity
Recombinant Human CTLA-4 Fc Chimera His-tag Protein Bioactivity
(2)
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Reactivity: Human
Source: CHO
Accession #: P16410
Applications: Bioactivity
Recombinant Human CTLA-4 Fc Chimera (CHO-expressed) Bioactivity
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Reactivity: Mouse
Source: NS0
Accession #: Q6GTR6
Applications: Bioactivity
Recombinant Mouse CTLA-4 Fc Chimera Protein Bioactivity
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Reactivity: Human
Details: Mouse IgG2A Monoclonal Clone #BNI3
Applications: IHC, ELISA, Flow, ICC/IF, IP
CTLA-4 Antibody (BNI3) ELISA: CTLA-4 Antibody (BNI3) [NB100-64849] -
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Reactivity: Human
Sensitivity: 0.13 pg/mL
Assay Range: 0.781-50 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma, Urine)
Applications: ELISA
CTLA-4 ELISA Standard Curve
(2)
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Recombinant Monoclonal Antibody For Research Use Only

Reactivity: Human
Details: Human IgG1 Monoclonal Clone #Hu111
Applications: Flow, CyTOF-ready
Detection of CTLA-4 antibody in HEK293 Human cell line Transfected with Human CTLA-4 and eGFP antibody by Flow Cytometry.
(2)
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Reactivity: Mouse
Assay Range: 125-8000 pg/mL
Applications: ELISA
Mouse CTLA-4 ELISA Standard Curve
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