7 results for "GABA-A Receptor Modulators" in 产品
GABA-A Receptor Modulators
GABAA Receptor Subunits
The majority of human endogenous GABAA receptors are composed of α1-, β2- and γ2-subunits in a 2:2:1 ratio (α2β2γ), however the exact subunit conformation is determined by the expression of different subunits in a given cell type. Some subunits are only expressed in specific brain areas, for example receptors containing the α2-subunit are found in regions where the α1-subunit is absent or expressed at low levels, such as the ...
Subtype-selective GABAA modulator
| Chemical Name: | (Z)-1-[2-Chloro-2-(2,4-dichlorophenyl)ethenyl]-1H-1,2,4-triazole hydrochloride |
| Purity: | ≥98% |
Positive allosteric modulator of GABAA receptors; displays subunit selectivity
| Chemical Name: | 4-Chloro-N-[2-(2-thienyl)imidazo[1,2-a]pyridin-3-yl]benzamide |
| Purity: | ≥97% |
GABA-mimetic; selectively interacts with β2- and β3-subunit containing GABAA receptors
| Chemical Name: | (R)-1-(1-Phenylethyl)-1H-imidazole-5-carboxylic acid ethyl ester |
| Purity: | ≥98% |
Potent positive allosteric modulator of GABAA receptors
| Alternate Names: | CCD 1042 |
| Chemical Name: | (3α,5α)-3-Hydroxy-3-methyl-pregnan-20-one |
Postitive allosteric modulator of GABAA receptors
| Chemical Name: | (3α,5β)-3-Hydroxy-pregnan-20-one |
Positive allosteric modulator of GABAA receptors
| Alternate Names: | 3a,5a-THPROG |
| Chemical Name: | (3α,5α)-3-Hydroxy-pregnan-20-one |
Positive modulator of GABAA receptors; endogenous neurosteroid
| Chemical Name: | (3α,5α)-3,21-Dihydroxypregnan-20-one |
| Purity: | ≥95% |