11 results for "GluR2 Small Molecules and Peptides" in 产品
GluR2 Small Molecules and Peptides
The GRIA2 gene encodes for glutamate receptor 2 with an isoform flop of 883 amino acids, 98 kDA, isoform flip of 883 amino acids and 98 kDA, and an isoform 3 of 901 amino acids long and 100 kDA. Glutamate receptors function as a ligand-gated ion channel in the central nervous system and are the predominant excitatory neurotransmitter receptors in the brain. GRIA2 has been researched regarding its role in Alzheimer's disease, multiple sclerosis, motor neuron disease, epilepsy, anorexia, bioplar disorder, and neurodegeneration. GRIA2 is involved in the CREB pathway, intracellular calcium signaling, glutamic acid signaling, and calcium channels as well as interacts with genes NSF, GRIA3, DLG4, GRID2, and SDCBP.
Selective non-NMDA iGluR antagonist
| Chemical Name: | 6,7-Dinitroquinoxaline-2,3-dione |
| Purity: | ≥98% |
Potent AMPA antagonist; more selective than CNQX (Cat. No. 0190)
| Chemical Name: | 2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide |
| Purity: | ≥98% |
Broad spectrum glutamatergic antagonist
| Chemical Name: | 4-Hydroxyquinoline-2-carboxylic acid |
| Purity: | ≥98% |
Positive allosteric modulator of AMPA receptors; inhibits AMPA desensitization
| Chemical Name: | 6-Chloro-3,4-dihydro-3-(5-norbornen-2-yl)-2H-1,2,4-benzothiazidiazine-7-sulfonamide-1,1-dioxide |
| Purity: | ≥98% |
Selective positive allosteric modulator of AMPA receptors
| Chemical Name: | N-[2-(4'-Cyano[1,1'-biphenyl]-4-yl)propyl]-2-propanesulfonamide |
| Purity: | ≥98% |
Selective non-competitive AMPA antagonist
| Chemical Name: | 4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-benzenamine dihydrochloride |
| Purity: | ≥98% |
Open-channel blocker of AMPA currents; selective for non-GluA2-containing receptors
| Chemical Name: | N,N,H,-Trimethyl-5-[(tricyclo[3.3.1.13,7]dec-1-ylmethyl)amino]-1-pentanaminiumbromide hydrobromide |
| Purity: | ≥98% |
Competitive non-NMDA iGluR antagonist
| Alternate Names: | MPQX |
| Chemical Name: | [[3,4-Dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]phosphonic acid |
| Purity: | ≥98% |
GluK1 antagonist; inhibits carbonic anhydrase (CA) II and IV; also positive allosteric modulator of GABAA receptors
| Alternate Names: | Topamax |
| Chemical Name: | 2,3:4,5-Bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate |
| Purity: | ≥98% |
Non-competitive non-NMDA iGluR antagonist
| Alternate Names: | GYKI 53773,LY 300164 |
| Chemical Name: | (8R)-7-Acetyl-5-(4-aminophenyl)-8,9-dihydro-8-methyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine |
| Purity: | ≥98% |
Positive allosteric modulator of AMPA receptors
| Chemical Name: | N-[(2S)-5-(6-Fluoro-3-pyridinyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide |
| Purity: | ≥98% |
