FiltersClear All
Integrin alpha V beta 3: Products
Integrin alpha V beta 3 (aVb3) is a heterodimeric adhesion protein that is highly expressed on endothelial cells and osteoclasts. Active cell surface aVb3 binds to the extracellular matrix proteins Vitronectin, Fibronectin, Fibrinogen, and Thrombospondin. It is essential for the maturation of osteoclasts and their bone resorption activity. Loss of aVb3 function during osteoclastogenesis causes osteoporosis. In addition, aVb3 enhances VEGF R2 mediated angiogenesis, IGF-1 mediated tumor cell invasiveness, and cell entry by several viruses.
Products:
Show More
"Integrin alpha V beta 3" has 24 results in Products.
Sort by:
Cyclo(-RGDfK)
Potent integrin inhibitor (αvβ3/αvβ6); also improves stem cell attachment in 3D cell culture scaffolds
page
of
1