4 results for "KCNN3" in 产品

KCNN3 Products

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. ...

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Selective negative modulator of KCa2 (SK) channels; inhibits SK currents

Chemical Name: N-[(1R)-1,2,3,4-Tetrahydro-1-naphthalenyl]-1H-benzimidazol-2-amine hydrochloride
Purity: ≥98%
Selective negative modulator of KCa2 (SK) channels; inhibits SK currents
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Positive modulator of KCa2 (SK) and KCa3.1 (IK) channels

Chemical Name: 6,7-Dichloro-1H-indole-2,3-dione 3-oxime
Purity: ≥98%
Positive modulator of KCa2 (SK) and KCa3.1 (IK) channels
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Negative allosteric modulator of KCa2 (SK) channels

Chemical Name: N-[2-[[(1R)-1-[3-(Trifluoromethyl)phenyl]ethyl]amino]-1H-benzimidazol-7-yl]acetamide hydrochloride
Purity: ≥98%
Negative allosteric modulator of KCa2 (SK) channels
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Potent negative modulator of KCa2.3 and KCa3.1 channels

Chemical Name: 1,3-Phenylenebis(methylene)bis(3-fluoro-4-hydroxybenzoate)
Purity: ≥98%
Potent negative modulator of KCa2.3 and KCa3.1 channels
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