6 results for "Kinesin Inhibitors" in 产品
Kinesin Inhibitors
Kinesin superfamily proteins (KIFs) are motor proteins that convert chemical energy, typically in the form of ATP, into mechanical force. They act upon microtubules to move vesicles and organelles within cells, cause the beating of flagella and cilia, and act within the mitotic and meiotic spindles to segregate replicated chromosomes to progeny cells.
Generally, kinesins mediate plus-end transport. Kinesins exist as dimers, with a catalytic 'head' domain and a 'stalk/tail' domain ...
Selective inhibitor of mitotic kinesin Eg5
| Chemical Name: | 1,2,3,4-Tetrahydro-4-(3-hydroxyphenyl)-6-methyl-2-thioxo-5-pyrimidinecarboxylic acid, ethyl ester |
| Purity: | ≥98% |
Kinesin-1 modulator; cell permeable
| Chemical Name: | 3,5-Dibromo-N'-((2,5-dimethyl-1-(3-nitrophenyl)-1H-pyrrol-3-yl)methylene)-4-hydroxybenzohydrazide |
| Purity: | ≥98% |
Potent and selective kinesin spindle protein (KSP) inhibitor; induces Mcl-1 degradation
| Alternate Names: | Filanesib |
| Chemical Name: | (2S)-2-(3-Aminopropyl)-5-(2,5-difluorophenyl)-N-methoxy-N-methyl-2-phenyl-1,3,4-thiadiazole-3(2H)-carboxamide trifluoroacetate |
| Purity: | ≥98% |
Potent kinesin spindle protein (KSP) inhibitor
| Chemical Name: | N-(3-Aminopropyl)-N-[(1R)-1-[7-chloro-4-oxo-3-(phenylmethyl)-4H-1-benzopyran-2-yl]-2-methylpropyl]-4-methylbenzamide hydrochloride |
| Purity: | ≥98% |
Selective and ATP-competitive Kif18A inhibitor
| Chemical Name: | 4-Chloro-2-nitro-1-(phenylsulfonyl)benzene |
| Purity: | ≥98% |
High affinity and selective allosteric KSP inhibitor
| Alternate Names: | SB 715992 |
| Chemical Name: | N-(3-Aminopropyl)-N-[(1R)-1-[7-chloro-3,4-dihydro-4-oxo-3-(phenylmethyl)-2-quinazolinyl]-2-methylpropyl]-4-methylbenzamide |
| Purity: | ≥98% |
