1 result for "NIK/MAP3K14 Small Molecules and Peptides" in 产品

NIK/MAP3K14 Small Molecules and Peptides

NIK (nuclear factor inducing kinase), also called MAP3K14 or MAP4K4, is a widely expressed 947 amino acid (aa), approximately 100 kDa cytoplasmic protein of the MAP kinase family. NIK participates in a non-canonical NFkappaB signaling cascade in which its activity and expression are elevated by TNF and related ligands. NIK activates IKK alpha/beta,...

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Potent NIK inhibitor

Chemical Name: 4-[3-[2-Amino-5-(2-methoxyethoxy)-4-pyrimidinyl]-1H-indol-5-yl]-2-methyl-3-butyn-2-ol
Purity: ≥98%
Potent NIK inhibitor
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