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8 results for "Nrf2 Small Molecules and Peptides" in 产品
Nrf2 Small Molecules and Peptides
NF-E2 related factor 2 (Nrf2) is a member of the cap 'n collar family of basic leucine zipper transcription factors. By binding antioxidant response elements (AREs), Nrf2 activates the transcription of genes encoding antioxidant and phase II drug-metabolizing enzymes needed to protect cells against oxidative damage. Transcriptional targets regulate...
Nrf2 signaling activator
| Chemical Name: | 1-(2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)-1H-imidazole |
| Purity: | ≥98% |
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Nrf2 inhibitor; phenotypically lethal
| Chemical Name: | N-[4-[2,3-Dihydro-1-(2-methylbenzoyl)-1H-indol-5-yl]-5-methyl-2-thiazolyl]-1,3-benzodioxole-5-acetamide |
| Purity: | ≥98% |
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Nrf2 activator; cell permeable
| Chemical Name: | 2-Methylenebutanedioic acid 4-octyl ester |
| Purity: | ≥98% |
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PGK1 inhibitor; activates Nrf2
| Chemical Name: | (3R,4S)-rel-4-[(4-Chlorophenyl)sulfonyl]tetrahydro-N-(2-methylpropyl)-3-thiophenamine-1,1-dioxide |
| Purity: | ≥98% |
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Nrf2 activator; inhibits Nrf2/Keap1 interaction
| Chemical Name: | (3S)-1-[4-[[(2,3,5,6-Tetramethylphenyl)sulfonyl]amino]-1-naphthalenyl]-3-pyrrolidinecarboxylic acid |
| Purity: | ≥98% |
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Nrf2 activator
| Chemical Name: | N-[5-(2-Furanyl)-1,3,4-oxadiazol-2-yl]-N'-(2-pyridinylmethyl)urea |
| Purity: | ≥98% |
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Inhibitor of Keap1- Nrf2 interaction
| Alternate Names: | LH601A |
| Chemical Name: | (1S,2R)-2-[[(1S)-1-[(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]-3,4-dihydro-2(1H)-isoquinolinyl]carbonyl]cyclohexanecarboxylic acid |
| Purity: | ≥98% |
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Covalent allosteric NRF2 inhibitor
| Chemical Name: | 1-[(3R)-3-[3-(4-Amino-1,3,5-triazin-2-yl)-5-chlorophenyl]-4-morpholinyl]-2-propen-1-one |
| Purity: | ≥98% |
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