79 results for "PAK1" in 产品
PAK1 Products
PAK (p21-activated kinases) are a family of serine/threonine kinases within the STE ser/thr protein kinase superfamily that play roles in various oncogenic signaling pathways. Cytoskeletal remodeling, motility, proliferation, and aberrant response to apoptosis and mitosis signals are among oncogenic cell functions coordinated by PAK family members. Group I (PAK1, PAK2 and PAK3, also called alpha, gamma and beta, respectively) contain auto-inhibitory and SH3 domains, in addition to the p21-binding and kinase domains present in Group II (PAK4, PAK6 and PAK7).
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![PAK1 Antibody - BSA Free Immunohistochemistry-Paraffin: PAK1 Antibody - BSA Free [NBP1-85802]](https://resources.rndsystems.com/images/products/nbp1-85802_rabbit-polyclonal-pak1-antibody-23420251573985.jpg "Immunohistochemistry-Paraffin: PAK1 Antibody - BSA Free [NBP1-85802]")
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 kappa Monoclonal Clone #4D1 |
| Applications: | IHC, WB, ELISA, ICC/IF, IP |
![Western Blot: PAK1 Antibody (4D1) [H00005058-M02]](https://resources.rndsystems.com/images/products/PAK1-Antibody-4D1-Western-Blot-H00005058-M02-img0011.jpg "Western Blot: PAK1 Antibody (4D1) [H00005058-M02]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Immunohistochemistry-Paraffin: PAK1 Antibody [NBP2-19680]](https://resources.rndsystems.com/images/products/PAK1-Antibody-Immunohistochemistry-Paraffin-NBP2-19680-img0006.jpg "Immunohistochemistry-Paraffin: PAK1 Antibody [NBP2-19680]")
Potent PAK inhibitor; brain penetrant and orally bioavailable
| Chemical Name: | 6-(2,4-Dichlorophenyl)-8-ethyl-2-[[3-fluoro-4-(1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one |
| Purity: | ≥98% |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: PAK1 AntibodyBSA Free [NBP3-04201]](https://resources.rndsystems.com/images/products/PAK1-Antibody-Western-Blot-NBP3-04201-img0003.jpg "Western Blot: PAK1 AntibodyBSA Free [NBP3-04201]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | ICC/IF |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR2113 |
| Applications: | IHC, WB, Flow, ICC/IF, IP |
Potent and selective PAK1 inhibitor
| Chemical Name: | (3S)-3-(2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-ylamino)-N-isopropylpyrrolidine-1-carboxamide |
| Purity: | ≥98% |
Negative control of NVS PAK1 1 (Cat. No. 6132)
| Chemical Name: | (3S)-3-(2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-ylamino)-N,N-dimethylpyrrolidine-1-carboxamide |
| Purity: | ≥98% |
Highly potent PAK1 and PAK2 inhibitor
| Chemical Name: | 2-[[[2-[[3-(Ethylsulfonyl)-4-(4-methyl-1-piperazinyl)phenyl]amino]-5-fluoro-4-pyrimidinyl][5-(hydroxymethyl)-2-methylphenyl]amino]methyl]benzonitrile |
| Purity: | ≥98% |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #6R3M5 |
| Applications: | WB, ICC/IF |
![Western Blot: PAK1 Antibody (6R3M5) [NBP3-15811]](https://resources.rndsystems.com/images/products/PAK1-Antibody-6R3M5-Western-Blot-NBP3-15811-img0002.jpg "Western Blot: PAK1 Antibody (6R3M5) [NBP3-15811]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #4F10 |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA |
![Western Blot: PAK1 Antibody [NB100-41389]](https://resources.rndsystems.com/images/products/PAK1-Antibody-Western-Blot-NB100-41389-img0001.jpg "Western Blot: PAK1 Antibody [NB100-41389]")
| Reactivity: | Human |
| Source: | Wheat germ |
| Applications: | WB, ELISA, AP, MA |
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: PAK1 AntibodyAzide and BSA Free [NBP2-95107]](https://resources.rndsystems.com/images/products/PAK1 "Western Blot: PAK1 AntibodyAzide and BSA Free [NBP2-95107]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: PAK1 [p Thr84] Antibody [NBP2-29511]](https://resources.rndsystems.com/images/products/PAK1-[p-Thr84]-Antibody-Western-Blot-NBP2-29511-img0002.jpg "Western Blot: PAK1 [p Thr84] Antibody [NBP2-29511]")
| Reactivity: | Human |
| Applications: | WB |
![Western Blot: PAK1 Overexpression Lysate [NBP2-09482]](https://resources.rndsystems.com/images/products/PAK1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-09482-img0001.jpg "Western Blot: PAK1 Overexpression Lysate [NBP2-09482]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: PAK1 [p Ser204] Antibody [NBP2-29665]](https://resources.rndsystems.com/images/products/PAK1-[p-Ser204]-Antibody-Western-Blot-NBP2-29665-img0001.jpg "Western Blot: PAK1 [p Ser204] Antibody [NBP2-29665]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | ICC/IF |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | ICC/IF |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | ICC/IF |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | ICC/IF |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | ICC/IF |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | ICC/IF |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | ICC/IF |