PDGF-D Proteins and Enzymes

Platelet-derived growth factor-D (PDGF-D) is a cytokine that associates into disulfide-linked homodimers that bind to PDGF R beta and trigger signaling through PDGF R beta homodimers and PDGF R alpha/beta heterodimers. It is secreted as a latent homodimer which is activated by proteolysis to release a bioactive disulfide-linked dimer. PDGF-DD is wi...