5 results for "PDK-1 Small Molecules and Peptides" in 产品

PDK-1 Small Molecules and Peptides

PDK-1 (Phosphoinositide-dependent Kinase-1), also called PKB kinase and PDPK1, is a member of the AGC group of serine/threonine kinases. Following insulin, growth factor, or pervanadate stimulation, PDK-1 phosphorylates and activates kinases from the Akt, p70 S6K, and RSK families, and is therefore involved in the regulation of cell proliferation a...

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PDPK1 (PDK1) inhibitor

Chemical Name: N-[3-[[5-Iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide
Purity: ≥98%
PDPK1 (PDK1) inhibitor
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Highly potent, selective PDPK1 (PDK1) inhibitor

Chemical Name: (3S,6R)-1-[6-(3-Amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-6-methyl-3-piperidinecarboxamide
Purity: ≥98%
Highly potent, selective PDPK1 (PDK1) inhibitor
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PDPK1 (PDK1) inhibitor; inhibits Akt signaling

Chemical Name: 2-Amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]acetamide
Purity: ≥98%
PDPK1 (PDK1) inhibitor; inhibits Akt signaling
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Potent and selective pyruvate dehydrogenase kinase (PDK) 1/2/3 inhibitor

Chemical Name: Bis(morpholinothiocarbonyl) disulfide
Purity: ≥98%
Potent and selective pyruvate dehydrogenase kinase (PDK) 1/2/3 inhibitor
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Potent and selective pyruvate dehydrogenase kinase (PDK) 1/2/3/4 inhibitor

Chemical Name: N-[4-(2-Chloro-5-methyl-4-pyrimidinyl)phenyl]-N-[[4-[[(2,2-difluoroacetyl)amino]methyl]phenyl]methyl]-2,4-dihydroxybenzamide
Purity: ≥98%
Potent and selective pyruvate dehydrogenase kinase (PDK) 1/2/3/4 inhibitor
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