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4 results for "PFKFB3 Inhibitors Small Molecules and Peptides" in 产品
PFKFB3 Inhibitors Small Molecules and Peptides
PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3) is an enzyme that plays a key role in the regulation of glycolysis in rapidly dividing cells, so is important in cancer metabolism and during development. PFKFB3 is present in a wide variety of tissues and is induced under hypoxic conditions. The enzyme is one of four PFKFB isozymes and differs from other family members in that it has a very high kinase:phosphatase activity ratio and is overexpressed in a range of cancer types. It ...
Potent and selective PFKFB3 inhibitor
| Chemical Name: | (2S)-N-[4-[[3-Cyano-1-[(3,5-dimethyl-4-isoxazolyl)methyl]-1H-indol-5-yl]oxy]phenyl]-2-pyrrolidinecarboxamide |
| Purity: | ≥98% |
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PFKFB3 inhibitor
| Chemical Name: | 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one |
| Purity: | ≥98% |
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Selective PFKFB3 inhibitor
| Chemical Name: | 1-(4-Pyridinyl)-3-(2-quinolinyl)-2-propen-1-one |
| Purity: | ≥98% |
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Potent and selective PFKFB3 inhibitor
| Chemical Name: | (2S)-N-[4-[[3-Cyano-1-(2-methylpropyl)-1H-indol-5-yl]oxy]phenyl]-2-pyrrolidinecarboxamide |
| Purity: | ≥98% |
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