54 results for "Phosphodiesterase 4A/PDE4A" in 产品
Phosphodiesterase 4A/PDE4A Products
Enzymes of the cAMP-dependent phosphodiesterase type 4 (PDE4) family are important in hydrolyzing cAMP produced by G-protein coupled receptor (GPCR) stimulated adenylyl cyclases. In brain, more than 90% of cAMP formed by the stimulation of GPCRs is hydrolyzed by PDE4 enzymes. PDE4 enzymes are also important molecular targets for a variety of therapeutic agents like antidepressants, anti-asthmatics, and anti-inflammatory drugs. PDE4 family comprises 4 genes (PDE4A, B, C and D); each exhibiting ...
PDE inhibitor (non-selective)
| Chemical Name: | 3,7-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione |
| Purity: | ≥98% |
| Reactivity: | Human, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1C8 |
| Applications: | IHC, WB, Flow, ICC/IF |
![Western Blot: Phosphodiesterase 4A/PDE4A Antibody (OTI1C8) [NBP2-02559]](https://resources.rndsystems.com/images/products/Phosphodiesterase-4A-PDE4A-Antibody-1C8-Western-Blot-NBP2-02559-img0023.jpg "Western Blot: Phosphodiesterase 4A/PDE4A Antibody (OTI1C8) [NBP2-02559]")
| Reactivity: | Human, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1C8 |
| Applications: | IHC, WB, Flow, ICC/IF, CyTOF-ready |
![Western Blot: Phosphodiesterase 4A/PDE4A Antibody (OTI1C8)Azide and BSA Free [NBP2-73376]](https://resources.rndsystems.com/images/products/Phosphodiesterase-4A-PDE4A-Antibody-OTI1C8-Azide-and-BSA-Free-Western-Blot-NBP2-73376-img0001.jpg "Western Blot: Phosphodiesterase 4A/PDE4A Antibody (OTI1C8)Azide and BSA Free [NBP2-73376]")
PDE4 inhibitor
| Chemical Name: | 4-(3-Butoxy-4-methoxyphenyl)methyl-2-imidazolidone |
| Purity: | ≥98% |
PDE4 inhibitor
| Chemical Name: | 4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one |
| Purity: | ≥98% |
Adenosine transport inhibitor
| Chemical Name: | 2,6-bis(Diethanolamino)-4,8-dipiperidinopyrimido[5,4-d]pyrimidine |
| Purity: | ≥98% |
PDE4 inhibitor. More active enantiomer of rolipram (Cat. No. 0905)
| Chemical Name: | (4R)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one |
| Purity: | ≥98% |
Potent and selective PDE4 inhibitor
| Alternate Names: | RP 73401 |
| Chemical Name: | 3-(Cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxybenzamide |
| Purity: | ≥98% |
PDE inhibitor (non-selective)
| Alternate Names: | KC-404 |
| Chemical Name: | 2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]-1-propanone |
| Purity: | ≥98% |
Orally active PDE4 inhibitor
| Chemical Name: | (R)-5-(4-Methoxy-3-propoxyphenyl)-5-methyl-2-oxazolidinone |
| Purity: | ≥98% |
| Reactivity: | Human |
| Source: | Sf 21 (baculovirus) |
| Accession #: | P27815 |
| Applications: | Enzyme Activity |
| Reactivity: | Human |
| Applications: |
| Reactivity: | Human, Mouse, Rat, Rabbit |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, IP |
![Western Blot: Phosphodiesterase 4A/PDE4A [p Ser686, p Ser688] Antibody [NB300-635]](https://resources.rndsystems.com/images/products/Phosphodiesterase-4A-PDE4A-[p-Ser686--p-Ser688]-Antibody-Western-Blot-NB300-635-img0001.jpg "Western Blot: Phosphodiesterase 4A/PDE4A [p Ser686, p Ser688] Antibody [NB300-635]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry: Phosphodiesterase 4A/PDE4A Antibody [NBP2-33388]](https://resources.rndsystems.com/images/products/PDE4A-Antibody-Immunohistochemistry-NBP2-33388-img0001.jpg "Immunohistochemistry: Phosphodiesterase 4A/PDE4A Antibody [NBP2-33388]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: Phosphodiesterase 4A/PDE4A Antibody [NBP2-55923]](https://resources.rndsystems.com/images/products/Phosphodiesterase-4A-PDE4A-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-55923-img0001.jpg "Immunocytochemistry/ Immunofluorescence: Phosphodiesterase 4A/PDE4A Antibody [NBP2-55923]")
| Reactivity: | Human |
| Applications: | WB |
![Western Blot: Phosphodiesterase 4A/PDE4A Overexpression Lysate [NBP2-09382]](https://resources.rndsystems.com/images/products/PDE4A-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-09382-img0001.jpg "Western Blot: Phosphodiesterase 4A/PDE4A Overexpression Lysate [NBP2-09382]")
| Reactivity: | Human |
| Details: | Mouse IgG Polyclonal |
| Applications: | WB |
![Western Blot: Phosphodiesterase 4A/PDE4A Antibody [H00005141-B01P]](https://resources.rndsystems.com/images/products/Phosphodiesterase-4A-PDE4A-Antibody-Western-Blot-H00005141-B01P-img0002.jpg "Western Blot: Phosphodiesterase 4A/PDE4A Antibody [H00005141-B01P]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Phosphodiesterase 4A/PDE4A Antibody [H00005141-D01P]](https://resources.rndsystems.com/images/products/Phosphodiesterase-4A-PDE4A-Antibody-Western-Blot-H00005141-D01P-img0001.jpg "Western Blot: Phosphodiesterase 4A/PDE4A Antibody [H00005141-D01P]")
| Reactivity: | Human |
| Source: | E. coli |
| Applications: | AC |
| Reactivity: | Human |
| Source: | E. coli |
| Applications: | AC |
| Reactivity: | Human, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1C8 |
| Applications: | IHC, WB, Flow, ICC/IF |
![Phosphodiesterase 4A/PDE4A Antibody (OTI1C8) [Alexa Fluor® 350]](https://resources.rndsystems.com/images/products/nbp2-73376af350_mouse-phosphodiesterase-4a-pde4a-mab-oti1c8-af350-28820231525516.jpg "Phosphodiesterase 4A/PDE4A Antibody (OTI1C8) [Alexa Fluor® 350] [NBP2-73376AF350] -")
| Reactivity: | Human, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1C8 |
| Applications: | IHC, WB, Flow, ICC/IF, CyTOF-ready |
![Phosphodiesterase 4A/PDE4A Antibody (OTI1C8) [CoraFluor™ 1]](https://resources.rndsystems.com/images/products/nbp2-73376cl1_mouse-phosphodiesterase-4a-pde4a-mab-oti1c8-corafluor-1-26920251751397.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1C8 |
| Applications: | IHC, WB, Flow, ICC/IF |
| Reactivity: | Human, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1C8 |
| Applications: | IHC, WB, Flow, ICC/IF |
![Phosphodiesterase 4A/PDE4A Antibody (OTI1C8) [mFluor Violet 500 SE]](https://resources.rndsystems.com/images/products/nbp2-73376mfv500_mouse-phosphodiesterase-4a-pde4a-mab-oti1c8-mfv500-se-57202313181023.png "Phosphodiesterase 4A/PDE4A Antibody (OTI1C8) [mFluor Violet 500 SE] -")
| Reactivity: | Human, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1C8 |
| Applications: | IHC, WB, Flow, ICC/IF |
![Phosphodiesterase 4A/PDE4A Antibody (OTI1C8) [mFluor Violet 610 SE]](https://resources.rndsystems.com/images/products/nbp2-73376mfv610_mouse-phosphodiesterase-4a-pde4a-mab-oti1c8-mfv610-se-6720239401717.png "Phosphodiesterase 4A/PDE4A Antibody (OTI1C8) [mFluor Violet 610 SE] [NBP2-73376MFV610] -")