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Poly(ADP-ribose) Polymerase Controls Small Molecules and Peptides

Poly (ADP-ribose) polymerase (PARP) catalyzes the post-translational modification of proteins by the addition of multiple ADP-ribose moieties. PARP transfers ADP-ribose from nicotinamide dinucleotide (NAD) to Glu/Asp residues on the substrate protein, and also polymerizes ADP-ribose to form long/branched chain polymers. Tankyrase proteins also display PARP activity.

PARP-1, one of 5 confirmed PARPs, is the most abundant and highly expressed PARP enzyme. PARP-1 detects and relocates to single ...

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Negative control for SK 575 (Cat. No. 7583)

Chemical Name: 12-(4-(2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)-N-(2-((2-(1-methyl-2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)-12-oxododecanamide
Purity: ≥98%
Negative control for SK 575 (Cat. No. 7583)
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