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5 results for "Post-translational Modification Inhibitors" in Products
Post-translational Modification Inhibitors
Post-translational modifications are chemical changes to a protein that occur after translation. They widen the range of functions of the final protein. Many of these protein modifications occur in the rough endoplasmic reticulum (RER). There are five types of post-translational modifications:
- Formation of disulfide bridges
- Proper folding
- Addition and processing of carbohydrates
- Specific proteolytic cleavage
- Assembly into multimeric proteins
Examples of specific ...
Inhibitor of KAT5 (Tip60)
| Chemical Name: | 5-(1,2-Thiazol-5-yldisulfanyl)-1,2-thiazole |
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Geranylgeranyltransferase I (GGTase I) inhibitor
| Chemical Name: | N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-(1-naphthalenyl)benzoyl]-L-leucine methyl ester trifluoroacetate salt |
| Purity: | ≥95% |
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Ubiquitin-activating enzyme (E1) inhibitor
| Chemical Name: | 4-[4-[(5-Nitro-2-furanyl)methylene]-3,5-dioxo-1-pyrazolidinyl]benzoic acid ethyl ester |
| Purity: | ≥98% |
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Reversible and non-competitive CBP/p300 inhibitor
| Chemical Name: | 5-[(4-Hydroxy-2,6-dimethylphenyl)methylene]-1,3-bis(phenylmethyl)-2,4,6(1H,3H,5H)-pyrimidinetrione |
| Purity: | ≥98% |
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Potent farnesyltransferase inhibitor
| Chemical Name: | 4-[2-[4-[(11R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide |
| Purity: | ≥98% |
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