6 results for "PPAR gamma Receptor Agonists" in 产品
PPAR gamma Receptor Agonists
Peroxisome proliferator-activated receptor gamma (PPARγ) is a member of the nuclear receptor family of ligand-activated transcription factors that heterodimerize with the retinoic X receptor (RXR) to regulate gene expression. PPARγ is located primarily in the adipose tissue, lymphoid tissue, colon, liver and heart and is thought to regulate adipocyte differentiation and glucose homeostasis. PPARγ has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. The human gene encoding PPARγ has been localized to chromosome 3 (3p25).
Selective PPARγ agonist; antidiabetic agent
| Chemical Name: | 5-[[4-[2-(5-Ethyl-2-pyridinyl)-ethoxy]phenyl]methyl]-2,4-thiazolidinedione hydrochloride |
| Purity: | ≥98% |
Potent and selective PPARγ agonist; antidiabetic agent
| Alternate Names: | BRL 49653 |
| Chemical Name: | 5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione |
| Purity: | ≥98% |
Selective PPARγ agonist. Orally active
| Chemical Name: | N-(2-Benzoylphenyl)-O-[2-(methyl-2-pyridinylamino)ethyl]-L-tyrosine hydrochloride |
| Purity: | ≥98% |
Selective PPARγ agonist; antidiabetic agent
| Alternate Names: | Rezulin |
| Chemical Name: | 5-[[4-[(3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl]-2,4-thiazolidinedione |
| Purity: | ≥98% |
Potent and selective PPARγ agonist; antidiabetic
| Alternate Names: | R 483,BM 131258 |
| Chemical Name: | 5-[[4-[2-(5-Methyl-2-phenyl-4-oxazolyl)ethoxy]benzo[b]thien-7-yl]methyl]-2,4-thiazolidinedione |
| Purity: | ≥98% |
PPARγ partial agonist
| Chemical Name: | 2,4-Dichloro-N-[3,5-dichloro-4-(3-quinolinyloxy)phenyl]benzenesulfonamide |
| Purity: | ≥98% |
