7 results for "Prostanoid Receptor Agonists Small Molecules and Peptides" in 产品
Prostanoid Receptor Agonists Small Molecules and Peptides
Prostanoid receptors are activated by the endogenous ligands prostaglandin (PG) D2, PGE2, PGF2α, PGH2, prostacyclin (PGI2) and thromboxane A2. Cyclooxygenase (COX) converts arachidonic acid to PGH2, from which the other prostaglandins are synthesized. Prostanoid receptors are a family of nine G-protein-coupled receptors that have distinct tissue distributions and actions.
- DP receptors (DP1-2) are coupled to Gαs. They are expressed in the small intestine, lung, stomach and uterus. ...
Promotes HSCs expansion; increases HSCs engraftment; also endogenous prostaglandin
| Alternate Names: | PGE2 |
| Chemical Name: | (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxo-prosta-5,13-dien-1-oic acid |
| Purity: | ≥98% |
Potent, stable thromboxane A2 (TP) receptor agonist
| Alternate Names: | 9,11-Dideoxy-9a,11a-methanoepoxy prostaglandin F2a |
| Chemical Name: | (5Z)-7-[(1R,4S,5S,6R)-6-[(1E,3S)-3-Hydroxy-1-octenyl]-2-oxabicyclo[2.2.1]hept-5-yl]-5-heptenoic acid |
| Purity: | ≥98% |
Synthetic prostaglandin E2 (Cat. No. 2296) derivative; regulates HSC development
| Chemical Name: | (5Z,11α,13E,15R)-11,15-Dihydroxy-16,16-dimethyl-9-oxo-prosta-5,13-dien-1oic acid |
| Purity: | ≥95% |
Endogenous IP receptor agonist
| Alternate Names: | Prostaglandin I2,Prostacyclin |
| Chemical Name: | (5Z,13E,8R,9S,11R,12R,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid sodium salt |
| Purity: | ≥98% |
Naturally-occurring prostanoid; potent vasoconstrictor
| Chemical Name: | 9α,11α,15S-Trihydroxy-prosta-5Z,13E-dien-1-oic acid tris(hydroxymethyl)aminomethane salt |
| Purity: | ≥98% |
Selective EP4 agonist
| Chemical Name: | (5R)-5-[(3S)-3-Hydroxy-4-phenyl-1-buten-1-yl]-1-[6-(2H-tetrazol-5-yl)hexyl]-2-pyrrolidinone |
| Purity: | ≥98% |
Potent prostacyclin (PGI2) analog
| Chemical Name: | 2-[[(1R,2R,3aS,9aS)-2,3,3a,4,9,9a-Hexahydro-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H-benz[f]inden-5-yl]oxy]acetic acid |
| Purity: | ≥98% |
